Simple and efficient isolation of cordycepin from culture broth of a Cordyceps militaris mutant
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- 作者：Mina Masuda1 ; Masanori Hatashita2 ; Shinya Fujihara1 ; Yu Suzuki3 ; Akihiko Sakurai1 ; 4 ; a_sakura@u-fukui.ac.jp" class="auth_mail" title="E-mail the corresponding author
- 关键词：Cordycepin ; Cordyceps militaris mutant ; Proton beam irradiation ; Crystallization ; Purification
- 刊名：Journal of Bioscience and Bioengineering
- 出版年：2015
- 出版时间：December 2015
- 年：2015
- 卷：120
- 期：6
- 页码：732-735
- 全文大小：647 K
文摘
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The culture broth of the Cordycepin militaris mutant G81-3 had high cordycepin concentration.
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Cordycepin was efficiently isolated from the culture broth by crystallization.
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The combination of temperature and pH shifts was the most effective crystallizing way.
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The purification by crystallization provided a highly purified cordycepin with a high yield.