Non-apoptotic functions of cell death effectors in inflammation and innate immunity

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• 作者：Alexandre Morizot ; Maya Saleh ; ^{maya.saleh@mcgill.ca}
• 关键词：Innate immunity ; Apoptosis ; Pattern recognition receptors ; Mitochondria
• 刊名：Microbes and Infection
• 出版年：2012
• 出版时间：November, 2012
• 年：2012
• 卷：14
• 期：14
• 页码：1241-1253
• 全文大小：789 K

文摘

Innate immunity and cell death are essential host defense mechanisms. Mounting evidence reveals that these processes are closely linked. The aim of this review is to highlight the close relationship between the pathways governing these processes, particularly how regulators of cell death control the induction of the innate immune response.