Microfluidic immunosensor for rapid and highly-sensitive salivary cortisol quantification

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• 作者：V. Pinto^a ; P. Sousa^a ; S.O. Catarino^a ; M. Correia-Neves^b ; ^c ; G. Minas^a ; ^{gminas@dei.uminho.pt}
• 关键词：Microfluidic immunosensor ; Colorimetric detection ; Lab-on-a-chip (LOC) ; Poly(dimethylsiloxane) ; Salivary cortisol
• 刊名：Biosensors and Bioelectronics
• 出版年：2017
• 出版时间：15 April 2017
• 年：2017
• 卷：90
• 期：Complete
• 页码：308-313
• 全文大小：598 K
• 卷排序：90

文摘

PDMS microfluidic immunosensor for salivary cortisol quantification was developed It integrates CMOS colorimetric detection for salivary cortisol quantification Microchannels geometry, immobilization method and immunoassay conditions were presented A detection limit of 18 pg/mL and a linear range of 0.01-20 ng/mL was achieved The salivary cortisol quantification was performed in 35 min