Stem Cell Harvesting after Bortezomib-Based Reinduction for Myeloma Relapsing after Autologous Transplantation: Results from the British Society of Blood and Marrow Transplantation/United Kingdom Myeloma Forum Myeloma X (Intensive) Trial
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- 作者：Christopher Parrish1 ; Curly T.C.M. Morris2 ; Cathy D. Williams3 ; David A. Cairns4 ; Jamie Cavenagh5 ; John A. Snowden6 ; John Ashcroft7 ; Jim Cavet8 ; Hannah Hunter9 ; Jenny M. Bird10 ; Anna Chalmers4 ; Julia M. Brown4 ; Kwee Yong11 ; Steve Schey12 ; Sally Chown13 ; Gordon Cook1 ; g.cook@leeds.ac.uk" class="auth_mail" title="E-mail the corresponding author ; on behalf of the National Cancer Research Institute Haemato-Oncology Clinical Studies Group
- 关键词：Myeloma ; Stem cell transplant ; Stem cell mobilization
- 刊名：Biology of Blood and Marrow Transplantation
- 出版年：2016
- 出版时间：June 2016
- 年：2016
- 卷：22
- 期：6
- 页码：1009-1016
- 全文大小：1088 K
文摘
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Stem cell harvesting from patients with myeloma who relapsed after autograft is explored.
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Fifty-two percent of patients without prior stored stem cells achieved successful harvest.
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Toxicity of remobilization was similar to that seen in first line mobilization.
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Remobilized cells were safe, effective, and reliable for second autograft.
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Outcomes from subsequent autograft are presented.