Experimental infection of chickens by a flagellated motile strain of Salmonella enterica serovar Gallinarum biovar Gallinarum
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- 作者：P.D. Lopesa ; O.C. Freitas Netoa ; oliveirocaetano@yahoo.com.br" class="auth_mail" title="E-mail the corresponding author ; D.F.A. Batistaa ; J. Denadaia ; M.F.F. Alarcona ; A.M. Almeidaa ; R.O. Vasconcelosa ; A. Settab ; P.A. Barrowc ; A. Berchieri Juniora
- 关键词：Domestic fowl ; Fowl typhoid ; Salmonella enterica biovar Gallinarum ; Pathogenicity ; Immune response
- 刊名：The Veterinary Journal
- 出版年：2016
- 出版时间：August 2016
- 年：2016
- 卷：214
- 期：Complete
- 页码：40-46
- 全文大小：3070 K
文摘
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Chicks were infected with a flagellated Salmonella enterica serovar Gallinarum strain (SG Fla+) or a wild-type strain (SG).
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SG Fla+ was less pathogenic for 5-day-old chicks than SG, inducing lower mortality and fewer lesions.
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SG Fla+ induced more CD4+ T lymphocytes and fewer CD8+ lymphocytes in the liver than SG.
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Levels of interleukin (IL)-6 and IL-18 mRNA were lower in chicks infected with SG Fla+ than chicks infected with SG.