Rapid detection of Mycobacterium tuberculosis
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- 作者：Walid Ben-Selma ; Imen Ben-Kahla ; Manel Marzouk ; Asma Ferjeni ; Samira Ghezal ; Moncef Ben-Said ; Jalel Boukadida
- 关键词：Diagnosis ; Mycobacterial antigens ; Mycobacterium tuberculosis ; Tuberculosis
- 刊名：Diagnostic Microbiology and Infectious Disease
- 出版年：2009
- 出版时间：November 2009
- 年：2009
- 卷：65
- 期：3
- 页码：232-235
- 全文大小：144 K
文摘
The usefulness of a new rapid diagnostic test (Patho-TB) using antibodies specific to mycobacterial antigens was evaluated for the rapid discrimination between pulmonary tuberculosis (TB) and non-TB pulmonary diseases on sputa. One hundred sputa collected from 79 active TB patients and from 21 patients with non-TB pulmonary diseases (asthma and chronic obstructive pulmonary disease) were enrolled into the study and tested for the presence of Mycobacterium tuberculosis by Ziehl–Neelsen smear, Patho-TB kit, and Löwenstein–Jensen culture. The sensitivity, specificity, positive predictive value, and negative predictive value of the Patho-TB test were 95 % , 100 % , 100 % , and 84 % , respectively. Patho-TB test is simple, quick, and easy to perform. Its sensitivity, specificity, and positive predictive value are satisfactory. Therefore, it could be used as a screening test in poorly equipped laboratories of TB endemic areas.