Late Effects after Umbilical Cord Blood Transplantation in Very Young Children after Busulfan-Based, Myeloablative Conditioning
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- 作者：Heather Allewelt1 ; heather.allewelt@dm.duke.edu" class="auth_mail" title="E-mail the corresponding author ; Jill El-Khorazaty2 ; Adam Mendizabal2 ; Mahsa Taskindoust1 ; Paul L. Martin1 ; Vinod Prasad1 ; Kristin Page1 ; Jean Sanders3 ; Joanne Kurtzberg1
- 关键词：Late effects ; Umbilical cord blood transplantation ; Myeloablative conditioning ; Busulfan
- 刊名：Biology of Blood and Marrow Transplantation
- 出版年：2016
- 出版时间：September 2016
- 年：2016
- 卷：22
- 期：9
- 页码：1627-1635
- 全文大小：759 K
文摘
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Virtually all patients experienced at least 1 significant late effect.
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A unique complication in the very young, dental problems were nearly universal.
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Short stature was commonly observed in patients with metabolic diseases (75%).
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Seventy-two percent of the assessable patients had normal pubertal development.
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Cognitive deficits were more commonly seen with metabolic diseases.