Nickel affects gill and muscle development in oriental fire-bellied toad (Bombina orientalis) embryos
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文摘
Nickel inhibited the development of external gill in B. orientalis embryos. The 168 h LC50 and EC50 values of nickel were 33.8 and 5.4 μM, respectively, in embryos. Nickel induced abnormal tail development of embryos. NF stage 26–31 was the most sensitive window for embryos to nickel exposure. Nickel affected the calcium-dependent myogenic gene expression in embryos.

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