Safety assessment for ethanol-based topical antiseptic use by health care workers: Evaluation of developmental toxicity potential
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- 作者：Andrew Maiera ; maierma@ucmail.uc.edu" class="auth_mail" title="E-mail the corresponding author ; Jerald L. Ovesena ; Casey L. Allena ; Raymond G. Yorkb ; Bernard K. Gadagbuic ; Christopher R. Kirmand ; Torka Poete ; Antonio Quiñ ; ones-Riveraf
- 关键词：Ethanol ; Safety assessment ; Hand sanitizers ; Dermal exposure ; Developmental toxicity ; Margin of exposure ; Healthcare workers ; Developmental toxicity ; Dose&ndash ; response ; Hand sanitizers ; Blood alcohol concentration
- 刊名：Regulatory Toxicology and Pharmacology
- 出版年：2015
- 出版时间：October 2015
- 年：2015
- 卷：73
- 期：1
- 页码：248-264
- 全文大小：1170 K
文摘
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A significant MOE exists compared to developmental toxicity effect levels.
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Blood alcohol levels from ABHS approximate consumption of non-alcoholic beverages.
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No significant risk of developmental toxicity is expected from ABHS use.