Control-release microcapsule of famotidine loaded biomimetic synthesized mesoporous silica nanoparticles: Controlled release effect and enhanced stomach adhesion in vitro
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- 作者：Jing Li ; Hongyu Wang ; Baixue Yang ; Lu Xu ; Nan Zheng ; Hongtao Chen ; Sanming Li ; li_sanming2013@163.com" class="auth_mail" title="E-mail the corresponding author
- 关键词：Mesoporous silica ; Control-release microcapsule ; Controlled release ; Stomach adhesion
- 刊名：Materials Science & Engineering C
- 出版年：2016
- 出版时间：1 January 2016
- 年：2016
- 卷：58
- 期：Complete
- 页码：273-277
- 全文大小：828 K
文摘
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Biomimetic synthesized mesoporous silica nanoparticles (B-MSNs) were used as carrier.
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Famotidine (FMT) loaded B-MSN exhibited a little controlled release effect.
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Control-release microcapsule of FMT loaded B-MSN controlled FMT release for 24 h.
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Stomach adhesion was enhanced by control-release microcapsule of FMT loaded B-MSN.