Antimicrobial activity of medicinal plants used by aborigines of Kalahandi, Orissa, India against multidrug resistant bacteria
文摘
Objective
To evaluate the antimicrobial potency of 20 non-edible and/or poisonous plants used by an aborigine tribe (Kandha) of Kalahandi district for infectious diseases.Methods
<p>Over a period of 5 months from two hospitals, 10 pathogenic bacteria (Staphylococcus aureus (S. aureus), Acinetobacter sp., Citrobacter freundii (C. freundii), Chromobacterium violeceum (C. violeceum), Escherichia coli (E. coli), Klebsiella sp., Proteus sp., Pseudomonas aeruginosa (P. aeruginosa), Salmonella typhi (S. typhi) and Vibrio cholerae (V. cholerae) were isolated to pure axenic cultures from clinical samples. Water and ethanolic extracts of leaves and barks were concentrated before monitoring antimicrobial activity by agar-well diffusion method.Results
<p>All bacterial strains isolated were multidrug resistant. Ethanolic extract of most plants had effective antimicrobial activity against all the isolated multidrug resistant bacteria. Plants, Anthocephalus cadamba (A. cadamba) and Pterocarpus santalinus (P. santalinus) had antibacterial effect on all used bacteria. Water extract of several plants too had effective antimicrobial activity for all bacteria used. Effective in vitro control of MDR strains of Acinetobacter sp., C. freundii, Proteus sp. and P. aeruginosa, the most potential urinary tract infection causing organisms by plant extracts of all major plant used herein is recorded. MDR C. violaceum isolated from skin lesions was found to be resistant to imipenem, piperacillin-tazobactam and amoxyclav and was found sensitive to 13 plant extracts.Conclusion
<p>Effective in vitro control of MDR strains of Acinetobacter sp., C. freundii, Proteus sp. and P. aeruginosa; enteropathogenic bacteria, E. coli, S. typhi, Klebsiella s p. and V. cholerae were found to be well controlled by all plant extracts used.
