Sulfamethoxazole abatement by means of ozonation

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• 作者：Renato F. Dantas ; S ; ra Contreras ; Carme Sans ; Santiago Esplugas
• 关键词：Pharmaceuticals ; Antibiotic ; Ozonation ; Sulfamethoxazole ; Biodegradability ; Kinetic
• 刊名：Journal of Hazardous Materials
• 出版年：2008
• 出版时间：11 February 2008
• 年：2008
• 卷：150
• 期：3
• 页码：790-794
• 全文大小：305 K

文摘

Sulfamethoxazole (SMX) is a bacteriostatic antibiotic largely used for diverse types of illness. Its widely use in humans and even in animals releases unmetabolized and active metabolites that have a strong potential in terms of effect in organisms. In this work, 200 mg L⁻¹ solution of sulfamethoxazole was treated by ozonation at different pH. Results showed that ozonation was proved to be an efficient method to degrade sulfamethoxazole. After 15 min of ozonation (corresponding dose = 0.4 g of ozone L⁻¹), the complete antibiotic abatement was almost achieved with just 10 % of mineralization. The biodegradability and toxicity of the ozonation intermediates were also studied. A biodegradability enhancement (increment of BOD₅/COD ratio) from 0 to 0.28 was observed after 60 min of ozonation. The acute toxicity of the intermediates was followed by the Microtox^® test and the toxicity profile showed a slight acute toxicity increment in the first stage of ozonation. The pH variation had an important role in the TOC and COD removal, promoting their growth with the increment of alkalinity. The second order kinetic constants for the ozonation of the SMX in an order of magnitude of 10⁵ L mol⁻¹ s⁻¹ were also determined for pH 5 and 7.