New chiral ligands derived from (+) and (−)-α-pinene for the enantioselective addition of diethylzinc to aldehydes

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• 作者：Gustavo Frensch^a ; Ricardo Labes^a ; Celso Luiz Wosch^a ; Laieli dos Santos Munaretto^a ; Kahlil Schwanka Salomé ; ^a ; Palimé ; cio G. Guerrero Jr.^b ; Francisco A. Marques^a ; ^{tic@ufpr.br" class="auth_mail" title="E-mail the corresponding author}
• 关键词：BCDMPBIHYVTOMY-FMSGJZPZSA-N ; OTBXPRJLIYBQHF-SNVBAGLBSA-N ; BBHSZOOWHIJKLU-XPCVCDNBSA-N ; JRQTWVSBROAISM-FMSGJZPZSA-N ; WKWGHWACXXWYHD-FMSGJZPZSA-N ; WMPDAIZRQDCGFH-UHFFFAOYSA-N
• 刊名：Tetrahedron Letters
• 出版年：2016
• 出版时间：20 January 2016
• 年：2016
• 卷：57
• 期：3
• 页码：420-422
• 全文大小：712 K

文摘

In this study, we synthesized five new chiral ligands from (+) and (−)-α-pinene, which were successfully employed in the stereoselective addition of diethylzinc to aldehydes, leading to secondary chiral alcohols in up to 99% yield and 94% e.e.