Multivariate analysis for the optimization of polysaccharide-based nanoparticles prepared by self-assembly
详细信息 查看全文
- 作者：Sara Pistone ; sara.pistone@farmasi.uio.no" class="auth_mail" title="E-mail the corresponding author ; Dafina Qoragllu ina_790@hotmail.com" class="auth_mail" title="E-mail the corresponding author ; Gro Smistad gro.smistad@farmasi.uio.no" class="auth_mail" title="E-mail the corresponding author ; Marianne Hiorth marianne.hiorth@farmasi.uio.no" class="auth_mail" title="E-mail the corresponding author
- 关键词：Polysaccharide nanoparticle ; Sodium alginate ; Ionic crosslinking ; Monodisperse ; Zinc chloride ; Polydispersity index
- 刊名：Colloids and Surfaces B: Biointerfaces
- 出版年：2016
- 出版时间：1 October 2016
- 年：2016
- 卷：146
- 期：Complete
- 页码：136-143
- 全文大小：1327 K
文摘
- •
Multivariate analysis facilitates the optimization of polysaccharide nanoparticles.
- •
Monodispersed particles are obtained by using a low polysaccharide concentration.
- •
Interaction between preparation factors was revealed through multivariate analysis.
- •
Factors’ interactions allow preparing particles at a high polysaccharide concentration.