Phenotypic differentiation does not affect tumorigenicity of primary human colon cancer initiating cells
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- 作者：Taronish D. Dubasha ; Christopher M. Hoffmanna ; Felix Oppela ; Klara M. Giesslera ; Sarah Webera ; Sebastian M. Dietera ; Jennifer Hü ; lleina ; Thorsten Zenza ; Friederike Herbsta ; Claudia Scholla ; Wilko Weichertb ; c ; e ; Wiebke Werftd ; Axel Bennerd ; Manfred Schmidta ; e ; Martin Schneiderf ; Hanno Glimma ; e ; Claudia R. Balla ; e ; claudia.ball@nct-heidelberg.de" class="auth_mail" title="E-mail the corresponding author
- 关键词：Colon cancer ; Tumor initiating cells ; Phenotypic differentiation
- 刊名：Cancer Letters
- 出版年：2016
- 出版时间：28 February 2016
- 年：2016
- 卷：371
- 期：2
- 页码：326-333
- 全文大小：2272 K
文摘
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Phenotypic differentiation in vitro does not affect tumorigenicity of spheroids.
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CRC TIC propagation is feasible in conditions favoring phenotypic differentiation.
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Phenotypic plasticity of primary CRC TIC enriched in spheroids.