Functional Correlates of childhood maltreatment and symptom severity during affective theory of mind tasks in chronic depression
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- 作者：Charlotte Hentzea ; 1 ; Charlotte.Hentze@med.uni-heidelberg.de" class="auth_mail" title="E-mail the corresponding author ; Henrik Walterb ; 1 ; Henrik.Walter@charite.de" class="auth_mail" title="E-mail the corresponding author ; Elisabeth Schrammc ; g ; elisabeth.schramm@uniklinik-freiburg.de" class="auth_mail" title="E-mail the corresponding author ; Sarah Drostd ; Sarah.Drost@ukb.uni-bonn.de" class="auth_mail" title="E-mail the corresponding author ; Dieter Schoepfe ; Dieter.Schoepf@ukb.uni-bonn.de" class="auth_mail" title="E-mail the corresponding author ; Thomas Fangmeierc ; thomas.fangmeier@uniklinik-freiburg.de" class="auth_mail" title="E-mail the corresponding author ; Margarete Matterna ; Margarete.Mattern@med.uni-heidelberg.de" class="auth_mail" title="E-mail the corresponding author ; Claus Normannc ; claus.normann@uniklinik-freiburg.de" class="auth_mail" title="E-mail the corresponding author ; Ingo Zobelf ; Ingo.Zobel@hs-fresenius.de" class="auth_mail" title="E-mail the corresponding author ; Knut Schnella ; Knut.Schnell@med.uni-heidelberg.de" class="auth_mail" title="E-mail the corresponding author
- 关键词：Persistent depressive disorder ; Early trauma ; Social cognition ; Mentalizing ; Amygdala ; Hippocampus ; fMRI
- 刊名：Psychiatry Research: Neuroimaging
- 出版年：2016
- 出版时间：30 April 2016
- 年：2016
- 卷：250
- 期：Complete
- 页码：1-11
- 全文大小：1466 K
文摘
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Enduring correlates of childhood maltreatment are detectable in chronic depression (CD).
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Affective ToM functions in CD are influenced by childhood maltreatment.
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Childhood maltreatment increases amygdala activation during affective ToM in CD.
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Heightened symptom severity in CD decreases hippocampal activation during affective ToM.