Topical distribution of acyclovir in normal equine skin and equine sarcoids: An in vitro study
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- 作者：M. Haspeslagha ; maarten.haspeslagh@ugent.be" class="auth_mail" title="E-mail the corresponding author ; L. Taevernierb ; A.A. Maesc ; L.E.M. Vlamincka ; B. De Spiegeleerb ; S.M. Croubelsc ; A.M. Martensa
- 关键词：Equine sarcoid ; Acyclovir ; Topical ; Transdermal
- 刊名：Research in Veterinary Science
- 出版年：2016
- 出版时间：June 2016
- 年：2016
- 卷：106
- 期：Complete
- 页码：107-111
- 全文大小：260 K
文摘
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Sarcoid skin is less permissive for acyclovir permeation compared to normal skin.
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Even in sarcoid skin, considerable acyclovir concentrations are found in the dermis.
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Research should now focus on the susceptibility of BPV DNA polymerase for acyclovir.