A Generic and Cell-Type-Specific Wound Response Precedes Regeneration in Planarians
详细信息 查看全文
- 作者：Omri Wurtzel1 ; 2 ; Lauren E. Cote1 ; 2 ; Amber Poirier1 ; 2 ; Rahul Satija3 ; 4 ; 5 ; Aviv Regev2 ; 3 ; Peter W. Reddien1 ; 2 ; reddien@wi.mit.edu" class="auth_mail" title="E-mail the corresponding author
- 刊名：Developmental Cell
- 出版年：2015
- 出版时间：7 December 2015
- 年：2015
- 卷：35
- 期：5
- 页码：632-645
- 全文大小：8402 K
文摘
- •
Injury activates a common wound-response transcriptional program
- •
Muscle, epidermis, and stem cells express most wound-induced genes
- •
A single gene, notum, is differentially induced at head- versus tail-facing injuries
- •
Injury-specific transcriptional changes emerge 24 hr after response initiation