Impact of fluid resuscitation on major adverse events following pancreaticoduodenectomy
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- 作者：Ramy Behman ; M.D.a ; b ; Sherif Hanna ; M.D.a ; b ; Natalie Coburn ; M.D. ; M.P.H.a ; b ; Calvin Law ; M.D. ; M.P.H.a ; b ; David P. Cyr ; M.D. ; M.Sc.a ; Jessica Truong ; M.D.a ; Jenny Lam-McCulloch ; M.Sc.a ; Paul McHardy ; M.D.c ; Jason Sawyer ; N.P. ; M.N.c ; Chris Idestrup ; M.D. ; M.Sc.c ; Paul J. Karanicolas ; M.D. ; Ph.D.a ; b ; paul.karanicolas@sunnybrook.ca" class="auth_mail" title="E-mail the corresponding author
- 关键词：Pancreaticoduodenectomy ; Pancreatic neoplasms ; Postoperative complications ; Fluid therapy
- 刊名：The American Journal of Surgery
- 出版年：2015
- 出版时间：November 2015
- 年：2015
- 卷：210
- 期：5
- 页码：896-903
- 全文大小：1006 K
文摘
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A cohort of patients undergoing pancreaticoduodenectomy was grouped by postoperative fluid resuscitation and compared for major adverse events.
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More positive fluid balance on postoperative days 0, 1, and 2 was significantly associated with incidence of major adverse events, ICU admission, and length of stay.
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The association between fluid balance and adverse events diminished over the postoperative period and was not present by postoperative day 3.
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Restrictive fluid resuscitation following pancreaticoduodenectomy may improve postoperative outcomes.