刊名:European Journal of Obstetrics and Gynecology and Reproductive Biology
出版年:2002
出版时间:April 10, 2002
年:2002
卷:102
期:1
页码:80-82
全文大小:61.9 K
文摘
Objective: To determine the effects of intraperitoneal Lipiodol™ and methylene blue in prevention of postsurgical adhesion formation. Study design: Thirty female rats were divided into three equal groups and a standard damage to provoke adhesion formation was made by laparotomy to each of them. Methylene blue and Lipiodol™ was administered intraperitoneally to the first and second groups, respectively; while the third group was taken as control and no additional intervention was made. Adhesions were scored by a second look laparotomy which was made 21 days after the first operation. Results: Adhesion scores of the second group (i.e. Lipiodol™ group) were significantly lower than that of controls. No significant differences were present between any other groups (i.e. methylene blue versus control and methylene blue versus Lipiodol™). Conclusion: Intraperitoneal administration of Lipiodol™ inhibits postsurgical adhesion formation in rats.