刊名:International Journal of Biological Macromolecules
出版年:2017
出版时间:March 2017
年:2017
卷:96
期:Complete
页码:578-588
全文大小:3954 K
卷排序:96
文摘
This may be the first report that TSC1 and TSC2 are involved in lung fibroblasts activation and fibrogenesis. MeCP2 can reduces TSC1 and TSC2 expression through DNA methylation. Repression of TSC1 and TSC2 mediated by MeCP2 regulates HELF cell differentiation and proliferation as myofibroblasts.