Optimization of PEG-salt aqueous two-phase systems by design of experiments
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- 作者：Anna Glyk ; Dö ; rte Solle ; Thomas Scheper ; Sascha Beutel ; beutel@iftc.uni-hannover.de" class="auth_mail" title="E-mail the corresponding author
- 关键词：PEG ; polyethylene glycol ; ATPS ; aqueous two-phase systems ; OFAT ; one-factor-at-a-time ; design of experiments ; DoE ; RSM ; response surface methodology ; FFD ; full factorial design ; fFD ; fractional factorial design ; ANOVA ; analysis of variance ; PBD ; Plackett&ndash ; Burman design ; CCD ; central composite design ; CCC ; central composite circumscribed ; CCF ; central composite face-centered ; BBD ; Box&ndash ; Behnken design ; MLR ; multiple linear regression ; F-test ; Fisher's statistical test ; t-test ; Student's
- 刊名：Chemometrics and Intelligent Laboratory Systems
- 出版年：2015
- 出版时间：15 December 2015
- 年：2015
- 卷：149
- 期：part_PA
- 页码：12-21
- 全文大小：671 K
文摘
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Characterization of a DoE process for optimization of ATPS by different steps
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Favored screening of significant factors in ATPS using factorial designs (FFD/fFD)
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Favored optimization of ATPS by RSM using central composite designs (CCC/CCF)
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Evaluation of experimental designs by statistical regression analysis and ANOVA
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Summary and evaluation of several statistical software packages used in ATPS