Adaptive evolution of Schizochytrium sp. by continuous high oxygen stimulations to enhance docosahexaenoic acid synthesis
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- 作者：Xiao-Man Sun ; Lu-Jing Ren ; renlujing@njtech.edu.cn" class="auth_mail" title="E-mail the corresponding author ; Xiao-Jun Ji ; Sheng-Lan Chen ; Dong-Sheng Guo ; He Huang ; biotech@njtech.edu.cn" class="auth_mail" title="E-mail the corresponding author
- 关键词：Schizochytrium sp ; Docosahexaenoic acid ; Adaptive evolution ; Enzyme activity
- 刊名：Bioresource Technology
- 出版年：2016
- 出版时间：July 2016
- 年：2016
- 卷：211
- 期：Complete
- 页码：374-381
- 全文大小：1135 K
文摘
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Adaptive laboratory evolution improves microalgae growth performance.
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High oxygen adaptation increased DHA yield and changed oxygen sensitivity.
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Adaptive evolution enhanced ICDH enzyme activities and reduced ACL enzyme activities.
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Endpoint strains can obtain higher DHA percentage in high oxygen supply.
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The squalene content of endpoint strains was reduced by 63.08%.