Tandem Hass??????Bender/Henry reaction for the synthesis of dimethylnitro alcohols from benzylic halides

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• 作者：Klein ; Thomas A. ; Schkeryantz ; Jeffrey M.
• 关键词：Hass– ; Bender reaction ; Henry reaction ; Tandem reaction ; TBAF
• 刊名：Tetrahedron Letters
• 出版年：2005
• 出版时间：July 4, 2005
• 年：2005
• 卷：46
• 期：27
• 页码：4535-4538
• 全文大小：112 K

文摘

Dimethylnitro alcohols are constructed in a one-pot process from benzylic halides and 2-nitropropane. The use of tetrabutylammonium fluoride (TBAF) as the promoter is essential for this tandem Hass–Bender/Henry reaction to proceed.