A C-type lectin that inhibits bacterial infection and facilitates viral invasion in black rockfish, Sebastes schlegelii
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- 作者：Yong Liua ; Ning-qiu Lib ; Xin-peng Zhaoa ; Bin Yuea ; Shu-wen Hea ; Zhi-xin Gaoa ; Shun Zhoua ; Min Zhanga ; lissazhang06@163.com" class="auth_mail" title="E-mail the corresponding author
- 关键词：Sebastes schlegelii ; C-type lectin ; Bacterial agglutination ; Antibacterial ; Facilitate viral infection
- 刊名：Fish & Shellfish Immunology
- 出版年：2016
- 出版时间：October 2016
- 年：2016
- 卷：57
- 期：Complete
- 页码：309-317
- 全文大小：1785 K
文摘
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A C-type lectin homolog (SsLec1) was identified and characterized.
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Expression of SsLec1 in tissues and macrophages could be induced by Listonella anguillarum.
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Recombinant SsLec1 purified from E. coli could recgonize and agglutinate Vibrio ichthyoenteri and Vibrio vulnificus.
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Recombinant SsLec1 could inhibit bacteria infection and facilitate viral infection in vivo.