Objective classification of glistenings in implanted intraocular lenses using Scheimpflug tomography

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• 作者：Heike Biwer ; MDAuthor Vitae ; Eva Schuber ; MD ; Marcus Honig ; BSc ; Bianca Spratte ; MD ; Martin Baumeister ; MD ; Thomas Kohnen ; MD ; PhD ; FEBO ; ^{kohnen@em.uni-frankfurt.de" class="auth_mail" title="E-mail the corresponding author}
• 刊名：Journal of Cataract & Refractive Surgery
• 出版年：2015
• 出版时间：December 2015
• 年：2015
• 卷：41
• 期：12
• 页码：2644-2651
• 全文大小：935 K

文摘

To evaluate whether ocular Scheimpflug tomography allows automated detection of glistenings in implanted intraocular lenses.

Setting

Department of Ophthalmology, Goethe University, Frankfurt, Germany.

Designs

Prospective, nonrandomized case series.

Methods

Patients who had phacoemulsification with implantation of various types of monofocal intra-ocular lenses (IOL) were examined under mydriasis for glistenings with the following 3 methods: subjective quantification with a rating scale during slitlamp examination, manual counting in slitlamp photographs, and using a purpose-written digital-image processing program for automatic counting of glistenings in Scheimpflug images. Examinations were performed by the same examiner at least 6 months after IOL implantation. Methods were tested for consistency with the Cohen κ coefficient and single-factor analysis of variance.

Results

The subjectively graded glistenings (n = 63 patients, 63 eyes) during slitlamp examination showed the same glistening grade as the manually counted glistenings in slitlamp photographs, with a moderate agreement (κ = 0.46). The glistening count derived from Scheimpflug images was not associated with the glistening grades determined through any of the slitlamp methods (P > .05).

Conclusion

Subjective glistening grading score showed a moderate agreement with counted score in slitlamp images. The Scheimpflug device used in this study did not provide images of required resolution to perform an automated counting of separate glistenings and thus classification.

Financial Disclosures

Drs. Biwer, Schmitt, Honig, Spratte, and Baumeister have no financial or proprietory interest in any material or method mentioned. Dr. Kohnen has received travel reimbursement and lecture fees and is a consultant to Abbott, Alcon, Thieme Compliance, Hoya, Rayner, Oculus, Schwind, and Zeiss.