Lipids and bariatric procedures part 1 of 2: Scientific statement from the National Lipid Association, American Society for Metabolic and Bariatric Surgery, and Obesity Medicine Association: EXECUTIVE SUMMARY

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• 作者：Harold E. Bays ; MD ; FTOS ; FACC ; FACE ; FNLA^a ; ^{hbaysmd@aol.com" class="auth_mail" title="E-mail the corresponding author} ; Peter H. Jones ; MD ; FNLA^b ; Terry A. Jacobson ; MD ; FACP ; FNLA^c ; David E. Cohen ; MD ; PhD^d ; Carl E. Orringer ; MD ; FACC ; FNLA^g ; Shanu Kothari ; MD ; FACS^h ; Dan E. Azagury ; MDⁱ ; John Morton ; MD ; MPH ; FACS ; FASMBS^j ; Ninh T. Nguyen ; MD ; FACS ; FASMBS^k ; Eric C. Westman ; MD ; MHS Diplomate ABOM^l ; Deborah B. Horn ; DO ; MPH Diplomate ABOM^m ; Wendy Scinta ; MD ; MSⁿ ; Craig Primack ; MD ; FACP ; FAAP Diplomate ABOM^o
• 关键词：Adiposopathy ; Bariatric surgery ; Bariatric procedure ; Cholesterol ; Lipids ; Obesity ; Scientific statement
• 刊名：Journal of Clinical Lipidology
• 出版年：2016
• 出版时间：January-February 2016
• 年：2016
• 卷：10
• 期：1
• 页码：15-32
• 全文大小：358 K

文摘

Bariatric procedures often improve lipid levels in patients with obesity. This 2-part scientific statement examines the potential lipid benefits of bariatric procedures and represents contributions from authors representing the National Lipid Association, American Society for Metabolic and Bariatric Surgery, and the Obesity Medicine Association. The foundation for this scientific statement was based on data published through June 2015. Part 1 of this 2-part scientific statement provides an overview of: (1) adipose tissue, cholesterol metabolism, and lipids; (2) bariatric procedures, cholesterol metabolism, and lipids; (3) endocrine factors relevant to lipid influx, synthesis, metabolism, and efflux; (4) immune factors relevant to lipid influx, synthesis, metabolism, and efflux; (5) bariatric procedures, bile acid metabolism, and lipids; and (6) bariatric procedures, intestinal microbiota, and lipids, with specific emphasis on how the alterations in the microbiome by bariatric procedures influence obesity, bile acids, and inflammation, which in turn, may all affect lipid levels. Included in part 2 of this comprehensive scientific statement will be a review of: (1) the importance of nutrients (fats, carbohydrates, and proteins) and their absorption on lipid levels; (2) the effects of bariatric procedures on gut hormones and lipid levels; (3) the effects of bariatric procedures on nonlipid cardiovascular disease risk factors; (4) the effects of bariatric procedures on lipid levels; (5) effects of bariatric procedures on cardiovascular disease; and finally (6) the potential lipid effects of vitamin, mineral, and trace element deficiencies that may occur after bariatric procedures. This document represents the executive summary of part 1.