Three SCMPBRs were operated at 72-, 24- and 6.5-h HRT.
Membrane fouling rate increased with lower operating HRTs through increased of SMPc.
At long HRT (72 h), hydrolysis was induced in cake layer formed on membrane surface.
At short HRT (6.5 h), fouling occur via cake layer compaction at high convection rate.
Macromolecular compound contributed more to membrane fouling than soluble compound.