In Epilepsy, BAD Is Not Really Bad

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• 作者：Elena Ziviani¹ ; Luca Scorrano¹ ; ² ; ^{luca.scorrano@unige.ch}
• 刊名：Neuron
• 出版年：2012
• 出版时间：24 May, 2012
• 年：2012
• 卷：74
• 期：4
• 页码：600-602
• 全文大小：150 K

文摘

In this issue of Neuron, show that fuel utilization by neuronal mitochondria, controlled by the Bcl-2 family member BAD, defines response to seizures. Control of K_ATP channels by mitochondrial metabolism might be a target for antiepileptic therapies.