Factors Determining Responses to Azacitidine in Patients with Myelodysplastic Syndromes and Acute Myeloid Leukemia with Early Post-Transplantation Relapse: A Prospective Trial

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• 作者：Janghee Woop>1p>p> ; p>p>2p> ; H. Joachim Deegp>1p>p> ; p>p>2p> ; Barry Storerp>1p>p> ; p>p>2p> ; Cecilia Yeungp>1p>p> ; p>p>2p> ; Min Fangp>1p>p> ; p>p>2p> ; Marco Mielcarekp>1p>p> ; p>p>2p> ; Bart L. Scottp>1p>p> ; p>p>2p>p> ; p>p>bscott@fredhutch.orgp>
• 关键词：Myelodysplastic syndromes ; Early post-transplantation relapse ; Azacitidine ; Clonal evolution
• 刊名：Biology of Blood and Marrow Transplantation
• 出版年：2017
• 出版时间：January 2017
• 年：2017
• 卷：23
• 期：1
• 页码：176-179
• 全文大小：417 K
• 卷排序：23

文摘

Azacitidine given early after transplantation for myelodysplastic syndromes is well tolerated Azacitidine induces remissions after early post-transplantation relapse in patients with myelodysplastic syndromes Early detection and intervention with azacitidine may improve outcome The clonal composition of myelodysplastic syndromes changes with relapse and during therapy