The evidence for low-dose CT screening of lung cancer

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• 作者：Kathleen Ruchalski ; ^{kruchalski@mednet.ucla.edu" class="auth_mail" title="E-mail the corresponding author} ; Antonio Gutierrez ; Scott Genshaft ; Fereidoun Abtin ; Robert Suh
• 关键词：NLST ; Lung cancer screening ; Nelson ; Lung-RADS
• 刊名：Clinical Imaging
• 出版年：2016
• 出版时间：March-April 2016
• 年：2016
• 卷：40
• 期：2
• 页码：288-295
• 全文大小：679 K

文摘

Lung cancer remains the leading cause of cancer-related death in the United States. An effective screening tool for early lung cancer detection has long been sought. Early chest radiograph and low-dose computed tomography (LDCT) screening trials were promising and demonstrated increased cancer detection. However, these studies were not able to improve lung cancer mortality. The National Lung Screening Trial resulted in decreased lung cancer mortality with LDCT screening in a high-risk population. Similar trials are currently underway in Europe. With LDCT now being widely implemented, it is paramount for radiologists to understand the evidence for lung cancer screening.