Initial Outcomes of a Lung Cancer Screening Program in an Integrated Community Health System

详细信息    查看全文

• 作者：Andrew T. Miller ; MD^a ; Patricia Kruger ; RN^b ; Karen Conner ; MD^c ; Teresa Robertson ; BS^d ; Braden Rowley ; BS^d ; William Sause ; MD^e ; John C. Ruckdeschel ; MD^b ; ^f ; Denitza P. Blagev ; MD^g ; ^h ; ^{denitza.blagev@imail.org" class="auth_mail" title="E-mail the corresponding author}
• 关键词：Lung cancer screening ; low-dose CT ; LDCT ; lung nodules ; pulmonary nodules ; lung cancer
• 刊名：Journal of the American College of Radiology
• 出版年：2016
• 出版时间：June 2016
• 年：2016
• 卷：13
• 期：6
• 页码：733-737
• 全文大小：237 K

文摘

Lung cancer screening with low-dose CT (LDCT) demonstrated reduced mortality in the National Lung Screening Trial, yet there is debate as to whether the reported efficacy can translate into comparable effectiveness with community-based screening. The authors’ purpose is to report the baseline patient characteristics and malignancy rate in the first 18 months after implementing a lung cancer screening program in an integrated community health system.

Methods

Patients were screened at 1 of 10 participating community-based centers within a 22-hospital system from 2013 to 2015. LDCT examinations were interpreted by 1 of 20 radiologists using structured reporting and an internally developed tracking system. Manual chart review was performed to ascertain the malignancy detection rate.

Results

A total of 357 patients were screened with LDCT. Of these, 80 patients were ineligible and 3 declined enrollment. The remaining 274 patients satisfied accepted screening criteria and were enrolled in the program. Malignancy was detected in a total of 11 enrollees (4.0%), 8 with lung cancer and 3 with extrapulmonary primary malignancies. Three patients (1.1%) were diagnosed with early-stage lung cancer and received definitive therapy.

Conclusions

Early-stage lung cancer was detected with LDCT screening in an integrated community health system at a rate similar to other trials.