We performed propensity matching for age, gender, baseline comorbidities, previous interventions, priority at hospital admission, frailty score, New York Heart Association class, EuroSCORE, and associated cardiac diseases. Next, the 30-day mortality and procedure-related morbidity of 162 patients (81 TAVI vs 81 AVR) with severe left ventricular systolic dysfunction (ejection fraction聽鈮ぢ?5%) were analyzed at the Italian National Institute of Health.
The 30-day mortality was comparable (P聽=聽.37) between the 2 groups. The incidence of periprocedural acute myocardial infarction (P聽=聽.55), low output state (P聽=聽.27), stroke (P聽=聽.36), and renal dysfunction (peak creatinine level, P聽=聽.57) was also similar between the 2 groups. TAVI resulted in significantly greater postprocedural permanent pacemaker implantation (P聽=聽.01) and AVR in more periprocedural transfusions (P聽<聽.01) despite a similar transfusion rate per patient (2.8 卤 3.7 for TAVI vs 4.4 卤 3.8 for AVR; P聽=聽.08). The postprocedural intensive care unit stay (median, 2 days after TAVI vs 3 days after AVR; P聽=聽.34), intermediate care unit stay (median, 0 days after both TAVI and AVR; P聽=聽.94), and hospitalization (median, 11 days after TAVI vs 14 days after AVR; P聽=聽.51) were comparable.
In patients with severe left ventricular systolic dysfunction, both TAVI and AVR are valid treatment options, with comparable hospital mortality and periprocedural morbidity. Comparisons of the mid- to long-term outcomes are mandatory.