Signal peptidase I processed secretory signal sequences: Selection for and against specific amino acids at the second position of mature protein

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• 作者：Yaramah M. Zalucki ; Michael P. Jennings ; ^{m.jennings@griffith.edu.au}
• 关键词：Signal peptidase I ; Signal peptide ; Cleavage site ; Secretion ; Amino acid bias
• 刊名：Biochemical and Biophysical Research Communications
• 出版年：2017
• 出版时间：12 February 2017
• 年：2017
• 卷：483
• 期：3
• 页码：972-977
• 全文大小：476 K
• 卷排序：483

文摘

Strong bias for acidic residues at P2′ only in bacterial species. No aromatic residues at P2′ in E. coli verified signal peptidase I set. Amino acid bias at mature protein help predict signal peptidase I cleavage.