ID 83 - Burst activity features of relay thalamic nuclei in patients with spasmodic torticollis

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• 作者：D. Devetiarov ; R. Medvednik ; A. Sedov
• 刊名：Clinical Neurophysiology
• 出版年：2016
• 出版时间：March 2016
• 年：2016
• 卷：127
• 期：3
• 页码：e80
• 全文大小：34 K

文摘

Research of burst activity at rest and during execution of functional tests and its possible connection with pathology of spasmodic torticollis.

Methods

Extracellular activity was obtained by microelectrode technique during stereotactic neurosurgical operations. Simultaneously, electromyographic data from neck and arm muscles were registered. Neuronal reactions to functional tests (verbally-ordered movement tasks) were also recorded.

Results

There was burst activity in Voi and Voa thalamic nuclei both at rest and during functional tests. In Voi tonic reactions generally were observed during movement execution and in after-effect and were connected with neck muscles movements. It could be caused by Voi’s cerebellar connections and posture functions. In Voa tonic and phasic reactions were observed during initiation, preparation, execution of movement and in after-effect, sometimes even on verbal command. These reactions weren’t connected only with neck muscles movements. It could be caused by Voa’s pallidal connections and execution of motor program. Significant prevalence of burst activity in surgical target (Voi) wasn’t observed.

Conclusion

Burst activity was common phenomenon in studied thalamic nuclei at rest and was reactive to functional tests. In general, burst activity wasn’t connected with pathology of spasmodic torticollis directly.

Key message

Thalamus, microelectrode, single unit activity, burst, spasmodic torticollis.