Intracranial hemorrhage due to late hemorrhagic disease in two siblings

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• 作者：Hü ; seyin Per ; Sefer Kumandaş ; Mehmet Akif &#xd6 ; zdemir ; Hakan Gü ; mü ; ş ; and Musa Karakukcu
• 关键词：late hemorrhagic disease ; vitamin K ; sibling
• 刊名：Journal of Emergency Medicine
• 出版年：2006
• 出版时间：July 2006
• 年：2006
• 卷：31
• 期：1
• 页码：49-52
• 全文大小：172 K

文摘

Deficiency of vitamin K predisposes to early, classic or late hemorrhagic disease of the newborn (HDN); late HDN may be associated with serious and life-threatening intracranial hemorrhage. Late HDN is characterized by intracranial bleeding in infants aged 1 week to 6 months due to severe vitamin K deficiency, occurring particularly in exclusively breastfed infants. Late HDN is still an important cause of mortality and morbidity in developing countries where vitamin K prophylaxis is not routinely practiced. In this study, we report on two siblings with intracranial bleeding who were fully breastfed without a routine supplementation of vitamin K. Vitamin K should be given to all newborns as a single, intramuscular dose of 1 mg.