Enhanced amperometric detection of metronidazole in drug formulations and urine samples based on chitosan protected tetrasulfonated copper phthalocyanine thin-film modified glassy carbon electrode
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- 作者：S. Meenakshia ; K. Pandiana ; jeevapandian@yahoo.co.uk" class="auth_mail" title="E-mail the corresponding author ; L.S. Jayakumarib ; jaya@mitindia.edu" class="auth_mail" title="E-mail the corresponding author ; S. Inbasekaranc
- 关键词：Differential pulse voltammetry ; Metronidazole ; Tetrasulfonated copper phthalocyanine ; Chitosan ; Urine samples
- 刊名：Materials Science & Engineering C
- 出版年：2016
- 出版时间：1 February 2016
- 年：2016
- 卷：59
- 期：Complete
- 页码：136-144
- 全文大小：1482 K
文摘
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A distinctive and reliable Chit/CuTsPc thin-film modified glassy carbon electrode was constructed and characterized.
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The Chit/CuTsPc modified electrode was used for electrocatalytic reduction and determination of MTZ.
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The developed sensor was highly accurate, low cost, pH dependent, selective and sensitive.
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Detection limit was found to be 0.41 nM from differential pulse voltammetry method.
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Voltammetric technique was effectively realistic to detect MTZ in drug formulations and urine samples.