OR.64. Increased Concentrations of the B Cell Chemokine CXCL13 and Increased Expression of the Th17 Transcription Factor RORC in Multiple Sclerosis

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• 作者：Finn Sellebjerg ; Martin Krakauer ; Jette Frederiksen ; Per Soelberg Sø ; rensen
• 关键词：Hot-dip galvanization ; Conversion coating ; Hydroxyapatite ; Bioactivity ; Phosphating
• 刊名：Clinical Immunology
• 出版年：2008
• 出版时间：2008
• 年：2008
• 卷：127
• 期：Supplement 1
• 页码：S26-S27
• 全文大小：45 K

文摘

As zinc phosphate acts as a versatile material for potential biomedical applications, it was modified into a thin layer coating for orthopaedic applications in the present study. A unique layering system consisting of pure substrate (316L SS), thick Fe–Zn alloy layers, thin ZnP layer on which a hydroxyapatite (HA) layer, was developed and studied. The composition, surface morphology and corrosion resistance characteristics of the layering system was evaluated. The stability of the multi-layered coating system consisting of ZnP inter layer, was evaluated by subjecting to different extent of dissolution in aggressive physiological media followed by allowing for re-growth in simulated body fluid (SBF). The coating system revealed good stability.