X-ray-responsive selenium nanoparticles for enhanced cancer chemo-radiotherapy
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- 作者：Bo Yua ; 1 ; Ting Liua ; 1 ; Yanxin Dub ; Zuandi Luoa ; Wenjie Zhenga ; Tianfeng Chena ; tchentf@jnu.edu.cn" class="auth_mail" title="E-mail the corresponding author
- 关键词：X-ray-responsive ; Selenium nanoparticles ; Radiosensitization ; Radiotherapy
- 刊名：Colloids and Surfaces B: Biointerfaces
- 出版年：2016
- 出版时间：1 March 2016
- 年：2016
- 卷：139
- 期：Complete
- 页码：180-189
- 全文大小：2883 K
文摘
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X-ray responsive PEG-SeNPs were facilely fabricated through PEG-templated synthesis method.
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The X-ray responsive property was attributed to its amorphous status.
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PEG-SeNPs sensitizes cancer cells to X-ray via induction of ROS-mediated apoptosis.