Anti-neoplastic selenium nanoparticles from Idiomarina sp. PR58-8
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- 作者：Pallavee Srivastava ; Meenal Kowshik ; meenal@goa.bits-pilani.ac.in" class="auth_mail" title="E-mail the corresponding author ; meenalkowshik@gmail.com" class="auth_mail" title="E-mail the corresponding author
- 关键词：SeNPs ; selenium nanoparticles ; XRD ; X-ray diffraction ; TEM ; transmission electron microscope ; ZMB ; Zobell&rsquo ; s marine broth ; MIC ; minimum inhibitory concentration ; 2 ; 3 DAN ; 2 ; 3 diaminonaphthalene ; EDS ; energy dispersive spectroscopy ; CFL ; cell free lysate ; TSH ; total thiol ; NP-SH ; non-protein thiol ; PB-SH ; protein-bound thiol ; DTNB ; 5 ; 5&prime ; dithio-bis (2-nitrobenzoic acid) ; MTT ; 3-(4 ; 5-dimethylthiazol-2-yl)-2 ; 5-diphenyltetrazolium bromide ; ROS ; reactive oxygen species ; DCFH-DA ; 2&prime ; 7&pr
- 刊名：Enzyme and Microbial Technology
- 出版年：2016
- 出版时间：December 2016
- 年：2016
- 卷：95
- 期：Complete
- 页码：192-200
- 全文大小：2218 K
文摘
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Intracellular SeNPs synthesized by Idiomarina sp. PR58-8.
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Spherical SeNPs with hexagonal crystal lattice observed by TEM and XRD analysis.
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Non-protein thiols confer selenite resistance to this isolate.
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Apoptosis induction in HeLa cell line by SeNPs responsible for their anti-neoplastic properties.