Electrically conductive gold nanoparticle-chitosan thermosensitive hydrogels for cardiac tissue engineering
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- 作者：Payam Baeia ; bAuthor Vitae ; Sasan Jalili-Firoozinezhadc ; dAuthor Vitae ; Sareh Rajabi-ZeletiaAuthor Vitae ; Mohammad Tafazzoli-ShadpourbAuthor Vitae ; Hossein Baharvanda ; e ; Baharvand@royaninstitute.org" class="auth_mail" title="E-mail the corresponding authorAuthor Vitae ; Nasser Aghdamia ; Nasser.Aghdami@royaninstitute.org" class="auth_mail" title="E-mail the corresponding authorAuthor Vitae
- 关键词：Chitosan ; Gold nanoparticles ; Thermosensitive hydrogel ; Electrical conductivity ; Cardiac tissue engineering
- 刊名：Materials Science & Engineering C
- 出版年：2016
- 出版时间：1 June 2016
- 年：2016
- 卷：63
- 期：Complete
- 页码：131-141
- 全文大小：2331 K
文摘
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Thermosensitive electro-conductive hydrogels were prepared from CS and GNPs.
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Gelation time and conductivity were tuned by varying concentration of GNPs.
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CS-2GNP with gelation time of 25.7 min and conductivity of 0.13 S·m− 1 was selected for in vitro studies.
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CS-2GNP supported active metabolism, migration and proliferation of MSCs.
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Expression of cardiac markers increased about two-fold in CS-2GNP compared to CS.