Clinical features and prognostic relevance of ovarian involvement in non-Hodgkin's lymphoma: A Consortium for Improving Survival of Lymphoma (CISL) report

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• 作者：Jina Yun ; Seok Jin Kim ; Jong Ho Won ; Chul Won Choi ; Hyeon Seok Eom ; Jin Seok Kim ; Min Kyoung Kim ; Jae-Yong Kwak ; Won Seog Kim ; Cheolwon Suh
• 关键词：Lymphoma ; Ovary ; Prognosis ; Rituximab ; Chemotherapy ; B-cell ; T-cell
• 刊名：Leukemia Research
• 出版年：2010
• 出版时间：September 2010
• 年：2010
• 卷：34
• 期：9
• 页码：1175-1179
• 全文大小：186 K

文摘

Fourteen patients had primary ovarian lymphoma, while eighteen patients had secondary ovarian involvement. There was no significant difference in survival rates between primary and secondary involvement with diffuse large B-cell lymphoma (DLBCL), the most common subtype. The 5-year overall survivals of primary and secondary involvement with DLBCL were 70.0 % and 59.3 % , respectively. The localized bilateral ovarian involvement showed poorer survival compared to stage III/IV patients with secondary ovarian involvement. Treatment outcomes of secondary ovarian involvement in non-Hodgkin's lymphoma were comparable to those of primary ovarian involvement, suggesting that ovarian involvement does not necessarily predict a worse prognosis for NHL patients.