Sequences of a co-existing SXT element, a chromosomal integron (CI) and an IncA/C plasmid and their roles in multidrug resistance in a Vibrio cholerae O1 El Tor strain
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- 作者：Ruibai Wanga ; b ; Jie Lia ; b ; Biao Kana ; b ; kanbiao@icdc.cn" class="auth_mail" title="E-mail the corresponding author
- 关键词：Multidrug resistance ; ESBL ; Vibrio cholerae ; SXT element ; IncA/C plasmid
- 刊名：International Journal of Antimicrobial Agents
- 出版年：2016
- 出版时间：September 2016
- 年：2016
- 卷：48
- 期：3
- 页码：305-309
- 全文大小：1093 K
文摘
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Identified a hybrid SXT element (ICEVchCHN1307), a new IncA/C plasmid (pVC1307) and a chromosome integron (CI).
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Provided their complete nucleotide sequence and clearly demonstrated their roles in antibiotic resistance.
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Powerful accumulation of drug resistance genes in Vibrio cholerae.
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More attention to the risk of spreading multiple drug resistances mediated by SXT and the IncA/C plasmid is required.