Premature ejaculation is highly prevalent, and has considerable effect on the quality of life.
The etiologies of lifelong and acquired premature ejaculation are different.
The pathophysiological mechanisms of premature ejaculation have not been entirely elucidated.
Current treatment options for premature ejaculation are oral, topical and behavioral therapies.
The significance of drug discovery, and the use of SSRIs for premature ejaculation are emphasized.