- 作者：Sergio Serni ; Gianni Vittori ; Lorenzo Masieri ; Mauro Gacci ; Alberto Lapini ; Giampaolo Siena ; Graziano Vignolini ; Andrea Mari ; Marco Carini ; Andrea Minervini
- 刊名：Urology
- 出版年：February, 2014
- 年：2014
- 卷：83
- 期：2
- 页码：331-338
- 全文大小：306 K
Objective
To compare surgical, pathological, short-term functional data, and complications of endoscopic robotic-assisted simple enucleation (ERASE) and open simple enucleation (OSE).Methods
We undertook matched-pair analysis (age, tumor size, and preoperative aspects and dimensions used for an anatomical [PADUA] score) of 392 patients treated with simple enucleation (SE) for T1a-T1b renal tumors in our department, including 160 patients in the OSE group and 80 in the ERASE group. Perioperative outcomes were compared with univariate analysis. Variables associated with warm ischemia time (WIT) >25 minutes, complications, and postoperative acute kidney dysfunction (AKD) were assessed with multivariate analysis.
Results
The groups were comparable in body mass index (BMI), comorbidity, and preoperative renal function. In the ERASE vs the OSE group, no significant differences resulted regarding WIT (18.5 vs 16.4 minutes, P聽= .5), complications, transfusion rate, reoperation rate for Clavien grade聽鈮? complications, and positive surgical margin rate (2.9% vs 2.1%, P聽= .63). In elective patients, no significant difference resulted in variation of estimated glomerular filtration rate from baseline (8.5 vs 13.9 mL/min, P聽= .17) and AKD. In the ERASE group, the clamping of renal pedicle was used with a lower frequency (P聽<.0001), with lower estimated blood loss (EBL), longer operative time, and a 1-day shorter hospitalization (P聽= .001). On the multivariate analysis, the surgical approach was not independently associated with WIT >25 minutes, postoperative complications, and AKD.
Conclusion
The ERASE is a feasible technique with a positive surgical margin rate comparable to OSE; it showed WIT and complication rates similar to the open approach, along with the advantages of mini-invasivity.