Potential antihyperglycaemic effect of myricetin derivatives from Syzygium malaccense
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- 作者：Bavani Arumugama ; Uma D. Palanisamyb ; Kek Heng Chuaa ; Umah Rani Kuppusamya ; umah@um.edu.my" class="auth_mail" title="E-mail the corresponding author
- 关键词：2-NBDG ; 2-(N-(7-nitrobenz-2-oxa-1 ; 3-diazol-4-yl)amino)-2-deoxyglucose ; AdipoQ ; adiponectin ; C1Q and collagen domain containing ; Akt1 ; RAC-alpha serine/threonine-protein kinase or thymoma viral proto-oncogene 1 ; CAT ; catalase ; DM ; diabetes mellitus ; DIM ; differentiation initiation media ; DMEM ; Dulbecco's modified eagle medium ; DPM ; differentiation progression media ; DMSO ; dimethylsulfoxide ; F2 ; myricetin derivative-rich fraction isolated from Syzygium malaccense ; FBS ; fetal bovine serum ; GPx1 ; gl
- 刊名：Journal of Functional Foods
- 出版年：2016
- 出版时间：April 2016
- 年：2016
- 卷：22
- 期：Complete
- 页码：325-336
- 全文大小：2322 K
文摘
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F2: myricetin derivatives of S. malaccense exhibited good antiglycaemic potential.
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F2 enhanced adipogenesis, 2-NBDG uptake and adiponectin secretion in adipocytes.
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F2 activated the insulin signalling pathway to exert its action.
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Activation of AMPK-adiponectin by F2 also contributed to significant glucose uptake.