We analyzed polymorphisms (SNPs) in the glucose-dependent insulinotropic polypeptide (GIP) and GIP receptor (GIPR) genes
Bone phenotypes included BMD, BMC, bone microarchitecture, fracture and in addition, serum GIP
two cohorts of women were investgated: OPRA (all women aged 75y, n=1044) and PEAK-25 (all women aged 25y; n=1061)
GIPR genotype was associated with lower ultrasound values in young women
GIP genotype was associated with lower ultrasound and femoral neck BMD and BMC in the elderly