Entrapping quercetin in silica/polyethylene glycol hybrid materials: Chemical characterization and biocompatibility
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- 作者：Michelina Catauroa ; michelina.catauro@unina2.it" class="auth_mail" title="E-mail the corresponding author ; Flavia Bollinoa ; Paola Nocerab ; Simona Piccolellab ; Severina Pacificob
- 关键词：Sol-gel hybrid materials ; Polyethylene glycol 400 ; Quercetin ; FT-IR spectroscopy ; Cytotoxicity
- 刊名：Materials Science & Engineering C
- 出版年：2016
- 出版时间：1 November 2016
- 年：2016
- 卷：68
- 期：Complete
- 页码：205-212
- 全文大小：1316 K
文摘
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SiO2/PEG quercetin organic-inorganic hybrids were synthesized via sol-gel.
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The formation of apatite on materials surface after SBF proved their bioactivity.
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Viability of NIH-3T3 cells was significantly increased by exposure to the hybrids.
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Viability of PC-12 and U-251 cell lines was not affected by new materials.
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SH-SY5Y cell proliferation was inhibited and their morphology was changed by hybrids.