- 作者：Tamer El-Khayat ; Gamal Hussein ; Hussein Shalaan ; Muneeb Alavi ; Gamal Aboul Nasr
- 刊名：Journal of the Saudi Heart Association
- 出版年：2012
- 出版时间：October, 2012
- 年：2012
- 卷：24
- 期：4
- 页码：285
- 全文大小：47 K
Background
Type II diabetes is a prominent risk factor for future cardiac events. Its impact on demographic data, mode of presentation and hospital outcome among a group of Saudi patients with ACS was prospectively studied.Methods
We studied 142 consecutive ASC pts. (91 diabetic) admitted to the CCU at NWAFH. Including UA, NSTEMI and STEMI.
Results
Diabetics were older (61 vs 51 y) [<em>pem> < 0.001], with higher BMI (30 vs 28) [<em>pem> < 0.05], hypertension (71 % vs 31 % ) [<em>pem> < 0.001], hyperlipedemia (54 % vs 28 % ) [<em>pem> < 0.001] and history of IHD (58 % vs 39 % ) [<em>pem> < 0.05]. There was no significant difference in mode of presentation between diabetics and non-diabetics, NSTEMI/UA (62 % vs 43 % ) and STEMI (36 % vs 47 % ) [PNS for both] or KILLIP class at admission. EF by 2D-echo was similar in both groups (37 ¡À 12 % vs 40 ¡À 13 % ) [PNS]. Pre-admission medications were more frequently prescribed to the diabetics, asprin (75 % vs 57 % ), clopidogrel (46 % vs 24 % ) [<em>pem> < 0.05] for both. Beta-blockers (56 % vs 28 % ) [<em>pem> = 0.001] and ACEi/ARBs (73 % vs 49 % ) [<em>pem> < 0.001]. Coronary angiography was offered equally to both groups (64 % vs 63 % ), while there was trend for more prevalence of multi-vessel disease (MVD) in diabetics (29 % vs 20 % ) [PNS]. As well as trend for more hospital mortality rate in diabetics (6.6 % vs 2 % ) [PNS].
Conclusions
Compared to non-diabetics ACS at NWAFH, diabetics are older, with more of hypertension, BMI, hyperlipedemia and IHD history. They were more frequently prescribed pre-admission medications. No impact of diabetes on mode of presentation (STEMI vs NSTEMI/UA) was found. Invasive approach is equally offered to both groups, with a trend for more prevalence of MVD and hospital mortality in the diabetic patients.