Extended antibiotic resistance in carbapenemase-producing Klebsiella pneumoniae: A case series

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• 作者：Christopher D. Walker ; MA^a ; Shivanjali Shankaran ; MD^b ; ^{shankas@evms.edu" class="auth_mail" title="E-mail the corresponding author}
• 关键词：Klebsiella pneumoniae ; drug resistance ; colistin
• 刊名：American Journal of Infection Control
• 出版年：2016
• 出版时间：1 September 2016
• 年：2016
• 卷：44
• 期：9
• 页码：1050-1052
• 全文大小：166 K

文摘

Infections caused by carbapenemase-producing Klebsiella pneumoniae resistant to tigecycline, colistin, or aminoglycosides are a growing health concern. In our retrospective chart review, we noted increased resistance to colistin compared with tigecycline, despite limited prior use of colistin. This may affect the choice of presumptive antibiotics used in these hard to treat infections. Improved infection control and antimicrobial stewardship practices are essential to prevent the spread of these multidrug-resistant organisms.